Peer-reviewed. Published. Presented.

Journal publications, conference presentations, press coverage, and company updates from across the Decode Health platform.

Peer-Reviewed Publications

  • Genome Biology: ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction

    First tool to extract immune gene family signatures – including HLA and KIR activity, diversity, and binding – from standard sequencing data, validated in MS and neuromyelitis optica cohorts across eight institutions.

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  • BMJ: Machine learning framework for early identification of high-spending Crohn’s disease patients using administrative claims

    First publication applying Decode’s platform to GI/Crohn’s disease, extending the validated methodology from MS into a new therapeutic area using administrative claims data.

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  • Communications Medicine: Multiple sclerosis risk stratification and healthcare cost prediction using machine learning

    Demonstrated that ML models predicted 90% of total four-month spend for top-cost MS patients vs. 42% with conventional methods. Open-access publication.

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  • The Journal of Molecular Diagnostics: Development of an End-to-End Total RNA Sequencing Quality Control Framework for Blood-Based Biomarker Discovery

    Establishes the QC methodology that underpins Decode’s RNA biomarker discovery pipeline. Companion to the Agilent Technologies webinar.

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Conference Presentations

  • Whole-blood RNA and plasma NfL correlations identify biomarker candidates and targetable pathways in MS and NMO

    2026 ACTRIMS Poster Presentation

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  • Multi-Analytical Integration of Public RNA-seq Data Reveals Blood-Based Sepsis Severity Biomarkers for Predictive Modeling

    2025 AMP Poster Presentation

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  • Application of an advanced data analytics platform to identify RNA biomarkers from publicly available data

    2024 AMP Poster Presentation

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  • Advanced multivariate analysis to discover candidate RNA biomarkers to distinguish relapsing-remitting multiple sclerosis and neuromyelitis optica

    2024 CMSC Poster Presentation

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  • Machine learning framework for multiple sclerosis risk stratification and healthcare cost prediction

    2024 CMSC Poster Presentation

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  • Unique RNA expression profiles associated with plasma neurofilament light chain measurements in relapsing-remitting multiple sclerosis and neuromyelitis optica

    2024 CMSC Poster Presentation

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Press & Company News

  • Vestigo publication logo

    Vestigo: ASPIRE data science internship provides mutual benefits to companies and students

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  • Decode Health Awarded $1.9 Million NIH Grant to Accelerate AI-Powered Insight for Multiple Sclerosis

    Decode Health Awarded $1.9 Million NIH Grant to Accelerate AI-Powered Insight for Multiple Sclerosis

    Two-year Small Business Innovation Research (SBIR) award strengthens the company’s mission to transform complex biomedical data into real-world solutions; the project will develop a blood-based, AI-driven readout of MS disease biology with Broad Clinical Labs, the Accelerated Cure Project for MS, and a broad network of industry and academic collaborators.

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  • Nashville Post logo

    Decode Health CEO Named to In Charge 2024: Health Care list

    Nashville gets a lot of attention for its successes — the cranes dotting the skyline, the big businesses moving to town. But the city is also facing significant challenges. Housing, a good education and a good wage are out of reach for too many Nashvillians. It’s up to those on our 2024 In Charge list to push the city toward a brighter future.

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  • 2024 Inc. Regionals Southeast

    Inc. Recognizes Decode Health as a Top 100 Company in the Southeast

    Inc., known for its insightful coverage of innovative businesses and start-up companies, acknowledges the fastest-growing private entities in the United States. Decode Health was recognized as one of Inc.’s top 100 companies of 2024, driving [read more…]

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  • Becker's health IT logo

    Decode taps new precision medicine data-sharing partner

    Precision medicine analytics company Decode Health is entering into a data-sharing partnership with data exchange platform Briya.

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  • Decode Health | Quest Diagnostics graphic

    Decode Health and Quest Diagnostics Joint Research Presented at American Academy of Neurology 2023 Annual Meeting

    The American Academy of Neurology (AAN) selected joint research by Decode Health and Quest Diagnostics for presentation at its 2023 Annual Meeting.

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