NIH-Funded Archives - Decode Health

Associations between perfluoroalkyl substances and multiple sclerosis in U.S. cohorts compared with NMOSD, MOGAD, and healthy controls

DecodeHealth2026-05-29T13:19:23-05:00

Decode contributed transcriptomic analysis and a portion of the expression cohort to this collaborative study linking serum PFHxS and PFOA exposure to multiple sclerosis risk in females. With the University of Miami Miller School of Medicine.

Associations between perfluoroalkyl substances and multiple sclerosis in U.S. cohorts compared with NMOSD, MOGAD, and healthy controlsDecodeHealth2026-05-29T13:19:23-05:00

Genome Biology: ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction

DecodeHealth2026-04-08T17:28:06-05:00

First tool to extract immune gene family signatures - including HLA and KIR activity, diversity, and binding - from standard sequencing data, validated in MS and neuromyelitis optica cohorts across eight institutions.

Genome Biology: ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstructionDecodeHealth2026-04-08T17:28:06-05:00

Whole-blood RNA and plasma NfL correlations identify biomarker candidates and targetable pathways in MS and NMO

DecodeHealth2026-03-19T19:59:04-05:00

2026 ACTRIMS Poster Presentation

Whole-blood RNA and plasma NfL correlations identify biomarker candidates and targetable pathways in MS and NMODecodeHealth2026-03-19T19:59:04-05:00

Multi-Analytical Integration of Public RNA-seq Data Reveals Blood-Based Sepsis Severity Biomarkers for Predictive Modeling

DecodeHealth2026-03-19T19:59:43-05:00

2025 AMP Poster Presentation

Multi-Analytical Integration of Public RNA-seq Data Reveals Blood-Based Sepsis Severity Biomarkers for Predictive ModelingDecodeHealth2026-03-19T19:59:43-05:00

The Journal of Molecular Diagnostics: Development of an End-to-End Total RNA Sequencing Quality Control Framework for Blood-Based Biomarker Discovery

DecodeHealth2026-03-19T19:47:07-05:00

Establishes the QC methodology that underpins Decode's RNA biomarker discovery pipeline. Companion to the Agilent Technologies webinar.

The Journal of Molecular Diagnostics: Development of an End-to-End Total RNA Sequencing Quality Control Framework for Blood-Based Biomarker DiscoveryDecodeHealth2026-03-19T19:47:07-05:00

Application of an advanced data analytics platform to identify RNA biomarkers from publicly available data

DecodeHealth2026-03-19T20:00:29-05:00

2024 AMP Poster Presentation

Application of an advanced data analytics platform to identify RNA biomarkers from publicly available dataDecodeHealth2026-03-19T20:00:29-05:00

The Journal of Molecular Diagnostics: Machine Learning Analysis Using RNA Sequencing to Distinguish Neuromyelitis Optica from Multiple Sclerosis and Identify Therapeutic Candidates

DecodeHealth2026-03-20T14:38:45-05:00

Quest Diagnostics and NIH/NIAID-funded study demonstrating RNA-seq-based ML classification of NMO vs. MS, with identification of actionable therapeutic targets.

The Journal of Molecular Diagnostics: Machine Learning Analysis Using RNA Sequencing to Distinguish Neuromyelitis Optica from Multiple Sclerosis and Identify Therapeutic CandidatesDecodeHealth2026-03-20T14:38:45-05:00

Advanced multivariate analysis to discover candidate RNA biomarkers to distinguish relapsing-remitting multiple sclerosis and neuromyelitis optica

DecodeHealth2026-03-19T20:01:49-05:00

2024 CMSC Poster Presentation

Advanced multivariate analysis to discover candidate RNA biomarkers to distinguish relapsing-remitting multiple sclerosis and neuromyelitis opticaDecodeHealth2026-03-19T20:01:49-05:00

Unique RNA expression profiles associated with plasma neurofilament light chain measurements in relapsing-remitting multiple sclerosis and neuromyelitis optica

DecodeHealth2026-03-19T20:02:45-05:00

2024 CMSC Poster Presentation

Unique RNA expression profiles associated with plasma neurofilament light chain measurements in relapsing-remitting multiple sclerosis and neuromyelitis opticaDecodeHealth2026-03-19T20:02:45-05:00

Development and evaluation of Total RNA sequencing quality controls for blood-based biomarker discovery

DecodeHealth2026-03-19T20:03:28-05:00

2023 AMP Poster Presentation

Development and evaluation of Total RNA sequencing quality controls for blood-based biomarker discoveryDecodeHealth2026-03-19T20:03:28-05:00

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