Peer-reviewed. Published. Presented.

Journal publications, conference presentations, whitepapers, press coverage, and company updates from across the Decode Health platform.

Peer-Reviewed Publications

  • Genome Biology: ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction

    First tool to extract immune gene family signatures – including HLA and KIR activity, diversity, and binding – from standard sequencing data, validated in MS and neuromyelitis optica cohorts across eight institutions.

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  • BMJ: Machine learning framework for early identification of high-spending Crohn’s disease patients using administrative claims

    First publication applying Decode’s platform to GI/Crohn’s disease, extending the validated methodology from MS into a new therapeutic area using administrative claims data.

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  • Communications Medicine: Multiple sclerosis risk stratification and healthcare cost prediction using machine learning

    Demonstrated that ML models predicted 90% of total four-month spend for top-cost MS patients vs. 42% with conventional methods. Open-access publication.

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  • The Journal of Molecular Diagnostics: Development of an End-to-End Total RNA Sequencing Quality Control Framework for Blood-Based Biomarker Discovery

    Establishes the QC methodology that underpins Decode’s RNA biomarker discovery pipeline. Companion to the Agilent Technologies webinar.

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Conference Presentations

  • Whole-blood RNA and plasma NfL correlations identify biomarker candidates and targetable pathways in MS and NMO

    2026 ACTRIMS Poster Presentation

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  • Multi-Analytical Integration of Public RNA-seq Data Reveals Blood-Based Sepsis Severity Biomarkers for Predictive Modeling

    2025 AMP Poster Presentation

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  • Application of an advanced data analytics platform to identify RNA biomarkers from publicly available data

    2024 AMP Poster Presentation

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  • Advanced multivariate analysis to discover candidate RNA biomarkers to distinguish relapsing-remitting multiple sclerosis and neuromyelitis optica

    2024 CMSC Poster Presentation

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  • Machine learning framework for multiple sclerosis risk stratification and healthcare cost prediction

    2024 CMSC Poster Presentation

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  • Unique RNA expression profiles associated with plasma neurofilament light chain measurements in relapsing-remitting multiple sclerosis and neuromyelitis optica

    2024 CMSC Poster Presentation

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Whitepapers & Reports

  • blue capsules

    Pre-Analytical RNA Integrity Assessment for Sequencing-Based Biomarker Discovery

    Technical whitepaper developed with Agilent Technologies. Companion to our JMD QC Framework publication and Agilent webinar on end-to-end QC processes for RNA biomarker discovery. Watch the webinar here.

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Press & Company News

  • Vestigo publication logo

    Vestigo: ASPIRE data science internship provides mutual benefits to companies and students

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  • Decode Health and Circular Genomics Announce a Research Collaboration to Advance Circular RNA Biomarkers in Multiple Sclerosis

    Decode Health and Circular Genomics Announce a Research Collaboration to Advance Circular RNA Biomarkers in Multiple Sclerosis

    The initiative pairs Decode Health’s AI-driven MS biomarker program with Circular Genomics’ circular RNA platform to support earlier detection and monitoring of multiple sclerosis

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  • Decode Health Awarded $1.9 Million NIH Grant to Accelerate AI-Powered Insight for Multiple Sclerosis

    Decode Health Awarded $1.9 Million NIH Grant to Accelerate AI-Powered Insight for Multiple Sclerosis

    Two-year Small Business Innovation Research (SBIR) award strengthens the company’s mission to transform complex biomedical data into real-world solutions; the project will develop a blood-based, AI-driven readout of MS disease biology with Broad Clinical Labs, the Accelerated Cure Project for MS, and a broad network of industry and academic collaborators.

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  • Nashville Post logo

    Decode Health CEO Named to In Charge 2024: Health Care list

    Nashville gets a lot of attention for its successes — the cranes dotting the skyline, the big businesses moving to town. But the city is also facing significant challenges. Housing, a good education and a good wage are out of reach for too many Nashvillians. It’s up to those on our 2024 In Charge list to push the city toward a brighter future.

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  • 2024 Inc. Regionals Southeast

    Inc. Recognizes Decode Health as a Top 100 Company in the Southeast

    Inc., known for its insightful coverage of innovative businesses and start-up companies, acknowledges the fastest-growing private entities in the United States. Decode Health was recognized as one of Inc.’s top 100 companies of 2024, driving [read more…]

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  • Becker's health IT logo

    Decode taps new precision medicine data-sharing partner

    Precision medicine analytics company Decode Health is entering into a data-sharing partnership with data exchange platform Briya.

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Blogs & Media

Blog Posts & Thought Leadership

Podcasts & Webinars

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