Peer-reviewed. Published. Presented.
Journal publications, conference presentations, whitepapers, press coverage, and company updates from across the Decode Health platform.
Peer-Reviewed Publications
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Genome Biology: ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction
First tool to extract immune gene family signatures – including HLA and KIR activity, diversity, and binding – from standard sequencing data, validated in MS and neuromyelitis optica cohorts across eight institutions.
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BMJ: Machine learning framework for early identification of high-spending Crohn’s disease patients using administrative claims
First publication applying Decode’s platform to GI/Crohn’s disease, extending the validated methodology from MS into a new therapeutic area using administrative claims data.
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Communications Medicine: Multiple sclerosis risk stratification and healthcare cost prediction using machine learning
Demonstrated that ML models predicted 90% of total four-month spend for top-cost MS patients vs. 42% with conventional methods. Open-access publication.
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The Journal of Molecular Diagnostics: Development of an End-to-End Total RNA Sequencing Quality Control Framework for Blood-Based Biomarker Discovery
Establishes the QC methodology that underpins Decode’s RNA biomarker discovery pipeline. Companion to the Agilent Technologies webinar.
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Conference Presentations
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Whole-blood RNA and plasma NfL correlations identify biomarker candidates and targetable pathways in MS and NMO
2026 ACTRIMS Poster Presentation
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Machine learning framework for multiple sclerosis risk stratification and healthcare cost prediction
2024 CMSC Poster Presentation
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Whitepapers & Reports
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Pre-Analytical RNA Integrity Assessment for Sequencing-Based Biomarker Discovery
Technical whitepaper developed with Agilent Technologies. Companion to our JMD QC Framework publication and Agilent webinar on end-to-end QC processes for RNA biomarker discovery. Watch the webinar here.
Download Whitepaper
Press & Company News
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Decode Health and Circular Genomics Announce a Research Collaboration to Advance Circular RNA Biomarkers in Multiple Sclerosis
The initiative pairs Decode Health’s AI-driven MS biomarker program with Circular Genomics’ circular RNA platform to support earlier detection and monitoring of multiple sclerosis
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Decode Health Awarded $1.9 Million NIH Grant to Accelerate AI-Powered Insight for Multiple Sclerosis
Two-year Small Business Innovation Research (SBIR) award strengthens the company’s mission to transform complex biomedical data into real-world solutions; the project will develop a blood-based, AI-driven readout of MS disease biology with Broad Clinical Labs, the Accelerated Cure Project for MS, and a broad network of industry and academic collaborators.
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Decode Health CEO Named to In Charge 2024: Health Care list
Nashville gets a lot of attention for its successes — the cranes dotting the skyline, the big businesses moving to town. But the city is also facing significant challenges. Housing, a good education and a good wage are out of reach for too many Nashvillians. It’s up to those on our 2024 In Charge list to push the city toward a brighter future.
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Inc. Recognizes Decode Health as a Top 100 Company in the Southeast
Inc., known for its insightful coverage of innovative businesses and start-up companies, acknowledges the fastest-growing private entities in the United States. Decode Health was recognized as one of Inc.’s top 100 companies of 2024, driving [read more…]
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Decode taps new precision medicine data-sharing partner
Precision medicine analytics company Decode Health is entering into a data-sharing partnership with data exchange platform Briya.
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Blogs & Media
Blog Posts & Thought Leadership
Podcasts & Webinars
- Webinar
Agilent Technologies: End-to-End QC Processes for RNA Biomarker Discovery
Co-presented with Agilent Technologies. Companion to the JMD QC Framework publication.
Watch - Podcast
The Future of Chronic Diseases – Decode Health
More Intelligent Tomorrow: a DataRobot Podcast
Listen - Podcast
Technology at the Turning Point of Healthcare Innovation – Chase Spurlock, Decode Health
Friends of Project Healthcare
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How AI and data help diagnose and treat disease – Chase Spurlock, Decode Health AI
The Healthcare Solutions Project
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Using machine learning to predict COVID-19 hotspots – Julia Polk & Chase Spurlock, Decode Health AI
The Healthcare Solutions Project
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